Inspired by Patients, Guided by Research

RE.GA.IN. uses evidence-based Regenerative Medicine procedures to return patients to the activities they love

Doctors

Treatments

Advanced, non-invasive therapies using cells and molecules from your blood, bone marrow or fat.

Doctors

Science

Founded upon decades of regenerative medicine research and rigorous testing.

Doctors

Doctors

RE.GA.IN. accredited doctors with expertise in the fields of orthopedics and sports medicine.

Doctors

News

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Conditions

At RE.GA.IN. we only treat conditions for which there is a clinical indication for regenerative medicine therapeutic benefit. To see if you’re a candidate, please select a problem area to the left.
cursor Select a Region to get Started
At RE.GA.IN. we only treat conditions for which there is a clinical indication for regenerative medicine therapeutic benefit. To see if you’re a candidate, please select a problem area to the left.
cursor
Select a Region to get Started
The most common cause of pain in the heel, this condition occurs when the Plantar Fascia, a critical ligament that connects your heel to the front of the foot, becomes damaged and inflamed. It can be particularly painful in mornings, up and down stairs, and after strenuous exercise or walking (but usually not during).
The Achilles tendon, which connects your heel bone to the calf muscles, is both the longest and most stressfully impacted tendon in the human body. Its overuse can cause micro-traumas which fail to heal, resulting in painful inflammation, swelling and stiffness.
Your knee holds cushioning cartilage to prevent the bones in your joint from touching. As this cartilage wears away, from age and other factors, patients can experience varying degrees of pain, swelling, stiffness and lack of mobility. This is the single most common form of arthritis.
Sometimes called “Jumper’s Knee”, this condition is the result of frequent or repeated trauma to the patella tendon, located just beneath the knee cap. These micro-traumas accumulate with age and frequency and can suffer from abnormal or inadequate healing.
Damage to your articular cartilage, or chondral, is known as a lesion. Chondral lesions can range from a soft spot or small tear in the cartilage to an extensive tear that may go to the bone. Under certain conditions, a piece of cartilage can rip off and cause further damage.
Most commonly seen in patients fifty and older, Osteoarthritis is the result of degradation of the cushioning cartilage between the hip’s ball and socket joint. Categorized by several levels of severity, patients can experience pain, cracking noises, and even locking of the joint.
Repetitive motions with your forearm, such as those demanded by racquet sports, weight-lifting and even chefs, can cause micro-tears in your tendon. If these fail to heal properly, patients can experience pain and even reduced grip strength over time.
Often caused by age or a traumatic injury, cushioning cartilage in the shoulder joint can degrade. This condition often presents as pain, stiffness and even cracking sounds as the shoulder joint is moved.
The shoulder joint is a shallow ball and socket joint, which relies upon the Rotator Cuff for strength and stability. Traumatic injuries or overuse can damage the tendon, and when these fail to properly heal, can result in prolonged inflammation, pain and limited mobility.
The intervertebral disc is composed of an external portion called anulus (formed by collagen) that covers the inner part, called nucleus pulposus (rich in water content). In old age or in the presence of pathological conditions, the anulus becomes fragile and more prone to collapse and tearing, while the nucleus pulposus loses its water content and becomes dehydrated, thus beginning the pathological process of degenerative discopathy.
It is an articulation located in the lower part of the spine, between the sacrum and the ileum (which is the bone that forms the pelvis), it is often underestimated but can be the cause of pain in about 15- 20% of patients with lumbar back pain. Most frequent problems are inflammatory pathologies, trauma outcomes or mechanical overload after spinal surgery (especially after L5-S1 fixation).
It is not always possible to accurately identify the cause of the lower back pain. In these cases, a treatment protocol involves the intervertebral disc and the articulations between vertebras (called Facet Joints).
Growth factors allow obtaining a physical effect of detachment of the membrane, significantly reducing the possibility of laceration in the surgical act. PRP also have antibacterial properties, they are able to control post-operative infections, which in many cases can compromise the success of the surgery.
Growth factors are used in endodontic surgery and in other surgical procedures, as in patients undergoing resective surgery for diphosphonate-related osteonecrosis. The growth factors are very effective in the regeneration of hard and soft periodontal tissues and allow very fast and efficient healing in oral surgery.
Rhizarthrosis, or arthritis of the saddle joint of the thumb, is a common problem affecting many patients, sometimes with an early onset. The constant movements of the thumb joint, as well as of the other fingers, provoke a continuous worsening of this condition, causing numbness, pain and reduced range of motion, deeply affecting the patients’ quality of life.
When a fracture does not heal properly, a condition called pseudarthrosis may occur. This can happen at all ages, the risk of developing it is 4%. Risk factors are represented by poor bone trophism, high energy trauma, exposed fractures, systemic pathologies of the patient.

Treatments

Treatments

Most of the time, your body is capable of spontaneous healing.

It’s only when these processes fail that patients turn to pharmaceuticals, low, or even highly-invasive surgeries.

At RE.GA.IN. we use your body's own healing agents to perform the jobs for which they were designed. All of our therapies are grounded in years of basic and clinical research at the Galeazzi Orthopedic Institute and worldwide.
Treatments

Most of the time, your body is capable of spontaneous healing.

It’s only when these processes fail that patients turn to pharmaceuticals, low, or even highly-invasive surgeries.

At RE.GA.IN. we use your body's own healing agents to perform the jobs for which they were designed. All of our therapies are grounded in years of basic and clinical research at the Galeazzi Orthopedic Institute and worldwide.

PRP

Info Our blood is comprised of red and white blood cells, platelets and plasma.

Platelet Rich Plasma

Using a simple blood draw and fast-spinning centrifuge, our clinicians are able to concentrate doses of your platelets for therapeutic use. Our platelets are commonly found in areas of injury, where they are responsible for preventing blood loss, controlling inflammation, and secreting growth factors which may trigger the natural healing response.

What to expect:
Patients will undergo a simple blood draw, performed in operating room for sterility purposes. Total procedure time 1 hour, second procedure commonly performed a week later.

BMAC Bone Marrow Aspirate Concentrate

Our Bone Marrow contains, although in low concentration, mesenchymal stem cells which are today considered a powerful tool to promote the restoration of tissue homeostasis (physiological condition) and help with tissue regeneration. RE.GA.IN clinicians are able to extract bone marrow directly from the patient's iliac crest or tibia, concentrate a therapeutic dose of mesenchymal cells and other growth factors to treat a variety of musculoskeletal conditions.

What to Expect: Under a proper anesthesiologic protocol , a certified surgeon will bone marrow from the patient’s iliac crest or tibia. Extracted Bone Marrow is washed, processed in the operating room and then injected into the site of injury. Total procedure time is 1 hour, followed by recovery period from the anesthetic treatment.

Adipose-tissue concentrate

Long thought to be a simple cushioning tissue, adipose (fat) is now regarded as one of the tissues that provides the greatest regenerative potential. The mesenchymal cells contained in the fat make it an excellent tool to promote the restoration of tissue homeostasis (physiological condition) by controlling inflammation, and promoting regeneration. Our doctors isolate adipose tissue through a mini-liposuction procedure (not to be confused with liposuction for aesthetic purposes), and use devices that mechanically break or separate the adipose tissue into an injectable formulation.
the adipose tissue into an injectable formulation.

What to Expect: Under a proper anesthesiologic protocol, a certified surgeon performs a mini-liposuction on the patient. Extracted fat is washed, broken down or separated, and then injected into the site of injury. Total procedure time is 1 hour, followed by the normal recovery times of the anesthetic treatment.

Science

Info Regenerative Medicine procedures are innovative, potent and yet, still evolving technology.

These procedures must be provided only by adequately trained personnel, in suitable spaces that guarantee their safety and sterility. The success of a regenerative medicine procedure also requires a scientific approach that few can provide.

Here at RE.GA.IN. we use our ample resources to ensure each procedure is delivered under the strictest standards

Benefits of the REGAIN approach include:

irccs

IRCCS

Proudly recognized by the Ministry of Health as a Scientific Institute of Hospitalization and Care. Scientific Institute of Medicine

supervision

Supervision

All procedures delivered under the supervision of dedicated RE.GA.IN scientists. Galeazzi Research

sterility

Sterility

Treatments performed in state of the art operating theaters to guarantee absolute sterility and safety.

complaint

Compliant

All treatments are in compliance with Italian and European regulations.

report

Patient report

All patients receive rich clinical reports detailing their treatment received.

database

Database

All data is stored in secure servers where RE.GA.IN can analyze and improve outcomes.

Doctors

_Doctor_

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Find out if you are a Candidate

To take the next step and find out whether you are a candidate for our regenerative procedures, fill out the contact form, and one of our patient liaisons will be in touch with you to help walk you through the next steps.

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